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KMID : 1022820190100010018
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Journal of Multiple Sclerosis and Neuroimmunology
2019 Volume.10 No. 1 p.18 ~ p.21
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Primary Central Nervous System Lymphoma Initially Misdiagnosed as Tumefactive Demyelinating Disease
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Kim Ji-Ah
Kim Yong-Sung
Park So-Hyun
Yoo Il-Han
Ahn Suk-Won
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Abstract
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Lesions of primary central nervous system lymphoma (PCNSL) are frequently misdiagnosed on brain MRI as tumefactive demyelinating diseases, such as multiple sclerosis (MS) or neuromyelitis optica (NMO). Biopsy may fail to detect tumor cells and indicate only inflammatory cell infiltration with demyelination. Both PCNSL and demyelinating diseases respond to corticosteroid therapy or improve spontaneously. Herein, we describe a patient with a PCNSL who was first diagnosed with tumefactive MS or NMO based on initial brain MRI and biopsy findings.
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KEYWORD
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Primary CNS lymphoma, Neuromyelitis optica, Multiple sclerosis
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